Acropolis To Amalfi

14 nights - 12 Oct 2026
Mediterranean

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CRUISE ONLY WAS £8819 pp £8378 PP
FLY CRUISE WAS £9734 pp £9247 PP
Prices based on 2 people sharing. Cruise only price does not include flights. Fly-cruise price may vary by chosen UK airport.

Where solo or family pricing is not available please call for more details.

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CRUISE ONLY WAS £10159 pp £9651 PP
FLY CRUISE WAS £11074 pp £10520 PP
Prices based on 2 people sharing. Cruise only price does not include flights. Fly-cruise price may vary by chosen UK airport.

Where solo or family pricing is not available please call for more details.

Image featured for illustrative purposes only

CRUISE ONLY WAS £12779 pp £12140 PP
FLY CRUISE WAS £13694 pp £13009 PP
Prices based on 2 people sharing. Cruise only price does not include flights. Fly-cruise price may vary by chosen UK airport.

Where solo or family pricing is not available please call for more details.

Image featured for illustrative purposes only

CRUISE ONLY WAS £18339 pp £17422 PP
FLY CRUISE WAS £19254 pp £18291 PP
Prices based on 2 people sharing. Cruise only price does not include flights. Fly-cruise price may vary by chosen UK airport.

Where solo or family pricing is not available please call for more details.

Image featured for illustrative purposes only

Want to add a hotel stay or change your flights?

Just call our team of cruise specialists to help build your dream cruise holiday today!

CRUISE ONLY Call
FLY CRUISE Call
Prices based on 3 people sharing. Cruise only price does not include flights. Fly-cruise price may vary by chosen UK airport.

Where solo or family pricing is not available please call for more details.

Image featured for illustrative purposes only

CRUISE ONLY Call
FLY CRUISE Call
Prices based on 3 people sharing. Cruise only price does not include flights. Fly-cruise price may vary by chosen UK airport.

Where solo or family pricing is not available please call for more details.

Image featured for illustrative purposes only

CRUISE ONLY Call
FLY CRUISE Call
Prices based on 3 people sharing. Cruise only price does not include flights. Fly-cruise price may vary by chosen UK airport.

Where solo or family pricing is not available please call for more details.

Image featured for illustrative purposes only

CRUISE ONLY £22047
FLY CRUISE Call
Prices based on 3 people sharing. Cruise only price does not include flights. Fly-cruise price may vary by chosen UK airport.

Where solo or family pricing is not available please call for more details.

Image featured for illustrative purposes only

Want to add a hotel stay or change your flights?

Just call our team of cruise specialists to help build your dream cruise holiday today!

CRUISE ONLY Call
FLY CRUISE Call
Prices based on 4 people sharing. Cruise only price does not include flights. Fly-cruise price may vary by chosen UK airport.

Where solo or family pricing is not available please call for more details.

Image featured for illustrative purposes only

CRUISE ONLY Call
FLY CRUISE Call
Prices based on 4 people sharing. Cruise only price does not include flights. Fly-cruise price may vary by chosen UK airport.

Where solo or family pricing is not available please call for more details.

Image featured for illustrative purposes only

CRUISE ONLY Call
FLY CRUISE Call
Prices based on 4 people sharing. Cruise only price does not include flights. Fly-cruise price may vary by chosen UK airport.

Where solo or family pricing is not available please call for more details.

Image featured for illustrative purposes only

CRUISE ONLY £26456
FLY CRUISE Call
Prices based on 4 people sharing. Cruise only price does not include flights. Fly-cruise price may vary by chosen UK airport.

Where solo or family pricing is not available please call for more details.

Image featured for illustrative purposes only

Want to add a hotel stay or change your flights?

Just call our team of cruise specialists to help build your dream cruise holiday today!

(Prices correct as of today’s date, are updated daily, are subject to change and represent genuine availability at time of update).

Cruise only holidays are financially protected by ABTA. Fly cruise holidays are financially protected by Regent Seven Seas Cruises under ATOL number 10297

Please click here to check the essential travel requirements before booking this cruise.

Our sister brand SixStarCruises specialise in luxury and ultra luxury cruise holidays. Click here to view this itinerary in full and speak to one of our specialist cruise concierge today. Our team are here to help you plan your perfect cruise holiday and guide you with first hand experience with more time on board than any other UK luxury travel agent.

Itinerary


Take a look at the shore excursions available for this itinerary.

1

Piraeus

It's no wonder that all roads lead to the fascinating and maddening metropolis of Athens. Lift your eyes 200 feet above the city to the Parthenon, its honey-color marble columns rising from a massive limestone base, and you behold architectural perfection that has not been surpassed in 2,500 years. But, today, this shrine of classical form dominates a 21st-century boomtown. To experience Athens—Athína in Greek—fully is to understand the essence of Greece: ancient monuments surviving in a sea of cement, startling beauty amid the squalor, tradition juxtaposed with modernity. Locals depend on humor and flexibility to deal with the chaos; you should do the same. The rewards are immense. Although Athens covers a huge area, the major landmarks of the ancient Greek, Roman, and Byzantine periods are close to the modern city center. You can easily walk from the Acropolis to many other key sites, taking time to browse in shops and relax in cafés and tavernas along the way. From many quarters of the city you can glimpse "the glory that was Greece" in the form of the Acropolis looming above the horizon, but only by actually climbing that rocky precipice can you feel the impact of the ancient settlement. The Acropolis and Filopappou, two craggy hills sitting side by side; the ancient Agora (marketplace); and Kerameikos, the first cemetery, form the core of ancient and Roman Athens. Along the Unification of Archaeological Sites promenade, you can follow stone-paved, tree-lined walkways from site to site, undisturbed by traffic. Cars have also been banned or reduced in other streets in the historical center. In the National Archaeological Museum, vast numbers of artifacts illustrate the many millennia of Greek civilization; smaller museums such as the Goulandris Museum of Cycladic Art Museum and the Byzantine and Christian Museum illuminate the history of particular regions or periods. Athens may seem like one huge city, but it is really a conglomeration of neighborhoods with distinctive characters. The Eastern influences that prevailed during the 400-year rule of the Ottoman Empire are still evident in Monastiraki, the bazaar area near the foot of the Acropolis. On the northern slope of the Acropolis, stroll through Plaka (if possible by moonlight), an area of tranquil streets lined with renovated mansions, to get the flavor of the 19th-century's gracious lifestyle. The narrow lanes of Anafiotika, a section of Plaka, thread past tiny churches and small, color-washed houses with wooden upper stories, recalling a Cycladic island village. In this maze of winding streets, vestiges of the older city are everywhere: crumbling stairways lined with festive tavernas; dank cellars filled with wine vats; occasionally a court or diminutive garden, enclosed within high walls and filled with magnolia trees and the flaming trumpet-shaped flowers of hibiscus bushes. Formerly run-down old quarters, such as Thission, Gazi and Psirri, popular nightlife areas filled with bars and mezedopoleia (similar to tapas bars), are now in the process of gentrification, although they still retain much of their original charm, as does the colorful produce and meat market on Athinas. The area around Syntagma Square, the tourist hub, and Omonia Square, the commercial heart of the city about 1 km (½ mi) northwest, is distinctly European, having been designed by the court architects of King Otho, a Bavarian, in the 19th century. The chic shops and bistros of ritzy Kolonaki nestle at the foot of Mt. Lycabettus, Athens's highest hill (909 feet). Each of Athens's outlying suburbs has a distinctive character: in the north is wealthy, tree-lined Kifissia, once a summer resort for aristocratic Athenians, and in the south and southeast lie Glyfada, Voula, and Vouliagmeni, with their sandy beaches, seaside bars, and lively summer nightlife. Just beyond the city's southern fringes is Piraeus, a bustling port city of waterside fish tavernas and Saronic Gulf views.

12 October 2026
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Piraeus
2

Mykonos

Although the fishing boats still go out in good weather, Mykonos largely makes its living from tourism these days. The summer crowds have turned one of the poorest islands in Greece into one of the richest. Old Mykonians complain that their young, who have inherited stores where their grandfathers once sold eggs or wine, get so much rent that they have lost ambition, and in summer sit around pool bars at night with their friends, and hang out in Athens in winter when island life is less scintillating. Put firmly on the map by Jackie O in the 1960s, Mykonos town—called Hora by the locals—remains the Saint-Tropez of the Greek islands. The scenery is memorable, with its whitewashed streets, Little Venice, the Kato Myli ridge of windmills, and Kastro, the town's medieval quarter. Its cubical two- or three-story houses and churches, with their red or blue doors and domes and wooden balconies, have been long celebrated as some of the best examples of classic Cycladic architecture. Luckily, the Greek Archaeological Service decided to preserve the town, even when the Mykonians would have preferred to rebuild, and so the Old Town has been impressively preserved. Pink oleander, scarlet hibiscus, and trailing green pepper trees form a contrast amid the dazzling whiteness, whose frequent renewal with whitewash is required by law. Any visitor who has the pleasure of getting lost in its narrow streets (made all the narrower by the many outdoor stone staircases, which maximize housing space in the crowded village) will appreciate how its confusing layout was designed to foil pirates—if it was designed at all. After Mykonos fell under Turkish rule in 1537, the Ottomans allowed the islanders to arm their vessels against pirates, which had a contradictory effect: many of them found that raiding other islands was more profitable than tilling arid land. At the height of Aegean piracy, Mykonos was the principal headquarters of the corsair fleets—the place where pirates met their fellows, found willing women, and filled out their crews. Eventually the illicit activity evolved into a legitimate and thriving trade network. Morning on Mykonos town's main quay is busy with deliveries, visitors for the Delos boats, lazy breakfasters, and street cleaners dealing with the previous night's mess. In late morning the cruise-boat people arrive, and the shops are all open. In early afternoon, shaded outdoor tavernas are full of diners eating salads (Mykonos's produce is mostly imported); music is absent or kept low. In mid- and late afternoon, the town feels sleepy, since so many people are at the beach, on excursions, or sleeping in their air-conditioned rooms; even some tourist shops close for siesta. By sunset, people have come back from the beach, having taken their showers and rested. At night, the atmosphere in Mykonos ramps up. The cruise-boat people are mostly gone, coughing three-wheelers make no deliveries in the narrow streets, and everyone is dressed sexy for summer and starting to shimmy with the scene. Many shops stay open past midnight, the restaurants fill up, and the bars and discos make ice cubes as fast as they can. Ready to dive in? Begin your tour of Mykonos town (Hora) by starting out at its heart: Mando Mavrogenous Square.

13 October 2026
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3

Bozcaada

14 October 2026
Bozcaada
4

Istanbul

The only city in the world that can lay claim to straddling two continents, Istanbul—once known as Constantinople, capital of the Byzantine and then the Ottoman Empire—has for centuries been a bustling metropolis with one foot in Europe and the other in Asia. Istanbul embraces this enviable position with both a certain chaos and inventiveness, ever evolving as one of the world’s most cosmopolitan crossroads. It’s often said that Istanbul is the meeting point of East and West, but visitors to this city built over the former capital of two great empires are likely to be just as impressed by the juxtaposition of old and new. Office towers creep up behind historic palaces, women in chic designer outfits pass others wearing long skirts and head coverings, peddlers’ pushcarts vie with battered old Fiats and shiny BMWs for dominance of the noisy, narrow streets, and the Grand Bazaar competes with modern shopping malls. At dawn, when the muezzin's call to prayer resounds from ancient minarets, there are inevitably a few hearty revelers still making their way home from nightclubs and bars. Most visitors to this sprawling city of more than 14 million will first set foot in the relatively compact Old City, where the legacy of the Byzantine and Ottoman empires can be seen in monumental works of architecture like the brilliant Aya Sofya and the beautifully proportioned mosques built by the great architect Sinan. Though it would be easy to spend days, if not weeks, exploring the wealth of attractions in the historical peninsula, visitors should make sure also to venture elsewhere in order to experience the vibrancy of contemporary Istanbul. With a lively nightlife propelled by its young population and an exciting arts scene that’s increasingly on the international radar—thanks in part to its stint as the European Capital of Culture in 2010—Istanbul is truly a city that never sleeps. It’s also a place where visitors will feel welcome: Istanbul may be on the Bosphorus, but at heart it’s a Mediterranean city, whose friendly inhabitants are effusively social and eager to share what they love most about it.

15 October 2026
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Istanbul
5

Lesbos

16 October 2026
6

Kusadasi

Whilst the busy resort town of Kusadasi offers much in the way of shopping and dining – not to mention a flourishing beach life scene, the real jewel here is Ephesus and the stunning ruined city that really take centre stage. With only 20% of the classical ruins having been excavated, this archaeological wonder has already gained the status as Europe’s most complete classical metropolis. And a metropolis it really is; built in the 10th century BC this UNESCO World Heritage site is nothing short of spectacular. Although regrettably very little remains of the Temple of Artemis (one of the seven wonders of the ancient world), the superb Library of Celsus’ façade is practically intact and it is one of life’s great joys to attend an evening performance in the illuminated ruins once all the tourists have left. The history of the city is fascinating and multi-layered and it is well worth reading up on this beforehand if a visit is planned. Another point of interest for historians would be the house of the Virgin Mary, located on the romantically named Mount Nightingale and just nine kilometres away from Ephesus proper. Legend has it that Mary (along with St. John) spent her final years here, secluded from the rest of the population, spreading Christianity. An edifying experience, even for non-believers. For the less historical minded amongst you, Kusadasi offers plenty in the way of activities. After a stroll through the town, jump in a taxi to Ladies’ Beach (men are allowed), sample a Turkish kebap on one of the many beachfront restaurants and enjoy the clement weather. If you do want to venture further afield, then the crystal clear beaches of Guzelcamli (or the Millipark), the cave of Zeus and the white scalloped natural pools at Pamukkale, known as Cleopatra’s pools, are definitely worth a visit.

17 October 2026
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Kusadasi
7

Cruising the Mediterranean Sea

18 October 2026
Cruising the Mediterranean Sea
8

Valletta

Malta's capital, the minicity of Valletta, has ornate palaces and museums protected by massive fortifications of honey-color limestone. Houses along the narrow streets have overhanging wooden balconies for people-watching from indoors. Generations ago they gave housebound women a window on the world of the street. The main entrance to town is through the City Gate (where all bus routes end), which leads onto Triq Repubblika (Republic Street), the spine of the grid-pattern city and the main shopping street. Triq Mercante (Merchant Street) parallels Repubblika to the east and is also good for strolling. From these two streets, cross streets descend toward the water; some are stepped. Valletta's compactness makes it ideal to explore on foot. City Gate and the upper part of Valletta are experiencing vast redevelopment that includes a new Parliament Building and open-air performance venue. The complex, completed mid-2013, has numerous pedestrian detours in place along with building noise and dust. Before setting out along Republic Street, stop at the tourist information office on Merchant Street for maps and brochures.

19 October 2026
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Valletta
9

Messina

Home to the Museo Regionale of Messina, known for featuring two of Caravaggio's paintings, the city is also famous for having been the capital of the ancient kingdom of Sicily.

20 October 2026
10

Sorrento

Sorrento may have become a jumping-off point for visitors to Pompeii, Capri, and Amalfi, but you can find countless reasons to love it for itself. The Sorrentine people are fair-minded and hardworking, bubbling with life and warmth. The tuff cliff on which the town rests is spread over the bay, absorbing sunlight, while orange and lemon trees waft their perfume in spring. Winding along a cliff above a small beach and two harbors, the town is split in two by a narrow ravine formed by a former mountain stream. To the east, dozens of hotels line busy Via Correale along the cliff—many have "grand" included in their names, and some indeed still are. To the west, however, is the historic sector, which still enchants. It's a relatively flat area, with winding, stone-paved lanes bordered by balconied buildings, some joined by medieval stone arches. The central piazza is named after the poet Torquato Tasso, born here in 1544. This part of town is a delightful place to walk through. Craftspeople are often at work in their stalls and shops and are happy to let you watch; in fact, that's the point. Music spots and bars cluster in the side streets near Piazza Tasso.

21 October 2026
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Sorrento
11

Civitavecchia

Italy's vibrant capital lives in the present, but no other city on earth evokes its past so powerfully. For over 2,500 years, emperors, popes, artists, and common citizens have left their mark here. Archaeological remains from ancient Rome, art-stuffed churches, and the treasures of Vatican City vie for your attention, but Rome is also a wonderful place to practice the Italian-perfected il dolce far niente, the sweet art of idleness. Your most memorable experiences may include sitting at a caffè in the Campo de' Fiori or strolling in a beguiling piazza.

22 October 2026
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12

La Spezia

La Spezia is sometimes thought of as nothing but a large, industrialized naval port en route to the Cinque Terre and Portovenere, but it does possess some charm, and it gives you a look at a less tourist-focused part of the Riviera. Its palm-lined promenade, fertile citrus parks, renovated Liberty-style palazzos, and colorful balcony-lined streets make parts of La Spezia surprisingly beautiful. Monday through Saturday mornings, you can stroll through the fresh fish, produce, and local-cheese stalls at the outdoor market on Piazza Cavour, and on Friday take part in the busy flea market on Via Garibaldi. There's also Porto Mirabello, a newly built tourist port with a pool club, shops, and several restaurants that overlook the fleet of super-yachts.

23 October 2026
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13

Monaco

The 202-hectare Principality of Monaco is located east of France’s Mediterranean coast. Known for its royal family, especially Prince Albert of Monaco, its casinos and racetracks and for being a wealthy state with no applied taxes. Monaco is reachable by air through the French airport of Nice Côte d'Azur, located approximately 16 miles from the principality.

24 October 2026
Monaco
14

Cruising the Mediterranean Sea

25 October 2026
Cruising the Mediterranean Sea
15

Barcelona

The infinite variety of street life, the nooks and crannies of the medieval Barri Gòtic, the ceramic tile and stained glass of Art Nouveau facades, the art and music, the throb of street life, the food (ah, the food!)—one way or another, Barcelona will find a way to get your full attention. The capital of Catalonia is a banquet for the senses, with its beguiling mix of ancient and modern architecture, tempting cafés and markets, and sun-drenched Mediterranean beaches. A stroll along La Rambla and through waterfront Barceloneta, as well as a tour of Gaudí's majestic Sagrada Famíliaand his other unique creations, are part of a visit to Spain's second-largest city. Modern art museums and chic shops call for attention, too. Barcelona's vibe stays lively well into the night, when you can linger over regional wine and cuisine at buzzing tapas bars.

26 October 2026
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Barcelona

*This holiday is generally suitable for persons with reduced mobility. For customers with reduced mobility or any medical condition that may require special assistance or arrangements to be made, please notify your Cruise Concierge at the time of your enquiry, so that we can provide specific information as to the suitability of the holiday, as well as make suitable arrangements with the Holiday Provider on your behalf.

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A truly all-inclusive holiday with regent seven seas. With FREE unlimited shore excursions, you can taste, tour and savour every moment in over 450 ports. The cruise line offers an unrivalled ultra-luxury experience from start to finish, with everything included - from exquisitely prepared cuisine to opulent all-balcony suites.

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Entertainment throughout the day and evening
WiFi included on-board
24-hour room service
Shuttle service to and from ports and airport where available
In-suite mini bar replenished daily
1:1.5 staff to guest ratio
Luxurious, all-suite accommodation
Return flights included from a choice of UK airports (fly cruise bookings only)
Gratuities included on-board
Self-service laundry
Unlimited beverages
Butler service for selected suites
Unlimited shore excursions

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