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Was £2372pp Now: £1715pp

Panama Canal: Mexico, Costa Rica & Colombia

Seattle | Victoria | San Francisco | San Francisco | Los Angeles | Cabo San Lucas | Acapulco | Puerto Quetzal | Puerto Caldera | Panama City | Panama City | Cartagena | Miami

  • 29 Sep 2025
  • 21 Nights
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Was £2372pp Now: £1715pp
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Was £2140pp Now: £1588pp

Panama Canal: Mexico, Costa Rica & Colombia

San Francisco | San Francisco | Los Angeles | Cabo San Lucas | Acapulco | Puerto Quetzal | Puerto Caldera | Panama City | Panama City | Cartagena | Miami

  • 02 Oct 2025
  • 18 Nights
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Was £2140pp Now: £1588pp
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Was £2034pp Now: £1477pp

Panama Canal: Mexico, Costa Rica & Colombia

Los Angeles | Cabo San Lucas | Acapulco | Puerto Quetzal | Puerto Caldera | Panama City | Panama City | Cartagena | Miami

  • 05 Oct 2025
  • 15 Nights
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Was £2034pp Now: £1477pp
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Was £2122pp Now: £1893pp

Panama Canal: Mexico & Colombia

Seattle | San Francisco | Los Angeles | Cabo San Lucas | Puerto Vallarta | Manzanillo | Acapulco | Puerto Quetzal | Puerto Caldera | Panama City | Panama City | Cartagena | Miami

  • 19 Oct 2025
  • 20 Nights
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Was £2122pp Now: £1893pp
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Cruise Only From:
Was £2016pp Now: £1709pp

Panama Canal: Mexico & Colombia

San Francisco | Los Angeles | Cabo San Lucas | Puerto Vallarta | Manzanillo | Acapulco | Puerto Quetzal | Puerto Caldera | Panama City | Panama City | Cartagena | Miami

  • 21 Oct 2025
  • 18 Nights
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Was £2016pp Now: £1709pp
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Cruise Only From:
Was £1960pp Now: £1656pp

Panama Canal: Mexico & Colombia

Los Angeles | Cabo San Lucas | Puerto Vallarta | Manzanillo | Acapulco | Puerto Quetzal | Puerto Caldera | Panama City | Panama City | Cartagena | Miami

  • 23 Oct 2025
  • 16 Nights
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Was £1960pp Now: £1656pp
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Cruise Only From:
Was £1499pp Now: £1295pp

Panama Canal: Mexico, Belize & Costa Rica

Miami | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami

  • 21 Nov 2025
  • 10 Nights
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Was £1499pp Now: £1295pp
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Cruise Only From:
Was £1460pp Now: £1298pp

Panama Canal: Mexico, Costa Rica & Belize

Miami | Georgetown | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami

  • 01 Dec 2025
  • 11 Nights
Cruise Only From:
Was £1460pp Now: £1298pp
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Cruise Only From:
Was £1460pp Now: £1203pp

Panama Canal: Mexico, Costa Rica & Belize

Miami | Georgetown | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami

  • 12 Dec 2025
  • 11 Nights
Cruise Only From:
Was £1460pp Now: £1203pp
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Cruise & Stay

Holiday prices from:
£3085pp

Panama Canal & Mexico Christmas Voyage with Miami Stay

Miami | Ocho Rios | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami

  • 20 Dec 2025
  • 14 Nights
Holiday prices from:
£3085pp
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Cruise Only From:
Was £1890pp Now: £1804pp

Panama Canal: Mexico, Costa Rica & Belize

Miami | Ocho Rios | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami

  • 22 Dec 2025
  • 11 Nights
Cruise Only From:
Was £1890pp Now: £1804pp
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Cruise Only From:
Was £1515pp Now: £1344pp

Panama Canal: Mexico, Costa Rica & Belize

Miami | Ocho Rios | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami

  • 02 Jan 2026
  • 11 Nights

Interest free Monthly Payments from JUST £249pp

Cruise Only From:
Was £1515pp Now: £1344pp
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Cruise Only From:
Was £1503pp Now: £1298pp

Panama Canal: Mexico, Costa Rica & Belize

Miami | Georgetown | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami

  • 04 Jan 2026
  • 11 Nights
Cruise Only From:
Was £1503pp Now: £1298pp
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Cruise Only From:
Was £1515pp Now: £1449pp

Panama Canal: Mexico, Jamaica & Costa Rica

Miami | Ocho Rios | Cartagena | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami

  • 13 Jan 2026
  • 11 Nights

Interest free Monthly Payments from JUST £225pp

Cruise Only From:
Was £1515pp Now: £1449pp
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Cruise Only From:
Was £1503pp Now: £1308pp

Panama Canal: Mexico, Costa Rica & Belize

Miami | Georgetown | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami

  • 19 Jan 2026
  • 11 Nights
Cruise Only From:
Was £1503pp Now: £1308pp
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Cruise Only From:
Was £1785pp Now: £1713pp

Caribbean: Harvest Caye, Cozumel & Roatan

New Orleans | Costa Maya | Harvest Caye | Roatán Island | Puerto Limón | Colón | Cartagena | Ocho Rios | Georgetown | Cozumel | New Orleans

  • 01 Feb 2026
  • 14 Nights
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Was £1785pp Now: £1713pp
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Cruise Only From:
Was £1718pp Now: £1649pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

San Diego | Cabo San Lucas | Acapulco | Puerto Quetzal | Puntarenas | Panama City | Panama City | Cartagena | Miami

  • 12 Feb 2026
  • 15 Nights
Cruise Only From:
Was £1718pp Now: £1649pp
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Cruise & Stay

Holiday prices from:
£2599pp

Caribbean Voyage with New Orleans

New Orleans | Costa Maya | Harvest Caye | Roatán Island | Puerto Limón | Colón | Cartagena | Montego Bay | Georgetown | Cozumel | New Orleans

  • 20 Feb 2026
  • 17 Nights
Holiday prices from:
£2599pp
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Return flights with luggage allowance
Two-night 4* hotel stay in Miami
14-night full-board cruise
Cruise Only From:
Was £1625pp Now: £1560pp

Caribbean: Harvest Caye, Cozumel & Roatan

New Orleans | Costa Maya | Harvest Caye | Roatán Island | Puerto Limón | Colón | Cartagena | Montego Bay | Georgetown | Cozumel | New Orleans

  • 22 Feb 2026
  • 14 Nights

Interest free Monthly Payments from JUST £209pp

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Was £1625pp Now: £1560pp
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Cruise Only From:
Was £2391pp Now: £2295pp

South America: Colombia & Ecuador

Miami | Santa Marta | Cartagena | Cartagena | Panama City | Manta | Salaverry | Callao | Callao

  • 27 Feb 2026
  • 12 Nights
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Was £2391pp Now: £2295pp
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Cruise Only From:
Was £1543pp Now: £1390pp

Panama Canal: Mexico, Costa Rica & Belize

Miami | Georgetown | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami

  • 04 Mar 2026
  • 11 Nights
Cruise Only From:
Was £1543pp Now: £1390pp
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Cruise Only From:
Was £2743pp Now: £2633pp

South America : Cabo & Trujillo

Callao | Salaverry | Manta | Panama City | Puntarenas | San Juan del Sur | Acajutla | Puerto Quetzal | Huatulco (Santa María Huatulco) | Acapulco | Manzanillo | Puerto Vallarta | Cabo San Lucas | San Diego

  • 11 Mar 2026
  • 17 Nights
Cruise Only From:
Was £2743pp Now: £2633pp
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Cruise Only From:
Was £1503pp Now: £1298pp

Panama Canal: Mexico, Costa Rica & Belize

Miami | Georgetown | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami

  • 15 Mar 2026
  • 11 Nights
Cruise Only From:
Was £1503pp Now: £1298pp
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Cruise Only From:
Was £1584pp Now: £1424pp

Panama Canal: Mexico, Costa Rica & Belize

Miami | Georgetown | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami

  • 26 Mar 2026
  • 11 Nights
Cruise Only From:
Was £1584pp Now: £1424pp
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Cruise Only From:
Was £2693pp Now: £2585pp

Panama Canal: Mexico & Costa Rica

Miami | Cartagena | Panama City | Panama City | Panama City | Puerto Caldera | Puerto Quetzal | Acapulco | Puerto Vallarta | Cabo San Lucas | San Francisco | San Francisco | Astoria | Victoria | Seattle

  • 11 Apr 2026
  • 22 Nights
Cruise Only From:
Was £2693pp Now: £2585pp
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Cruise Only From:
Was £2550pp Now: £2448pp

Panama Canal: Mexico & Costa Rica

Miami | Cartagena | Panama City | Panama City | Panama City | Puerto Caldera | Puerto Quetzal | Acapulco | Puerto Vallarta | Cabo San Lucas | San Francisco | San Francisco

  • 11 Apr 2026
  • 18 Nights
Cruise Only From:
Was £2550pp Now: £2448pp
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Cruise Only From:
Was £1872pp Now: £1797pp

Panama Canal: Mexico, Costa Rica & Panama

Miami | Cartagena | Colón | Colón | Puerto Caldera | Puerto Quetzal | Puerto Vallarta | Cabo San Lucas | Los Angeles | Seattle

  • 25 Apr 2026
  • 18 Nights
Cruise Only From:
Was £1872pp Now: £1797pp
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Cruise Only From:
Was £1806pp Now: £1733pp

Panama Canal: Mexico & Costa Rica

Miami | Cartagena | Colón | Colón | Puerto Caldera | Puerto Quetzal | Puerto Vallarta | Cabo San Lucas | Los Angeles

  • 25 Apr 2026
  • 15 Nights
Cruise Only From:
Was £1806pp Now: £1733pp
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Cruise Only From:
Was £1769pp Now: £1698pp

Panama Canal: Mexico, Costa Rica & Colombia

Los Angeles | Cabo San Lucas | Acapulco | Puerto Quetzal | Puerto Caldera | Panama City | Panama City | Cartagena | Ocho Rios | Miami

  • 07 Oct 2026
  • 16 Nights
Cruise Only From:
Was £1769pp Now: £1698pp
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Cruise Only From:
Was £2080pp Now: £1996pp

Panama Canal: Mexico & Jamaica

Los Angeles | Cabo San Lucas | Acapulco | Puerto Quetzal | Puerto Caldera | Panama City | Panama City | Cartagena | Falmouth | Miami

  • 13 Oct 2026
  • 16 Nights
Cruise Only From:
Was £2080pp Now: £1996pp
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Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. SixStarCruises acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.

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